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ハルビン獣医研究所 研究成果

論文発表

  1. Watanabe T, Watanabe S, Shinya K, Kim JH, Hatta M, Kawaoka Y. Viral RNA polymerase complex promotes optimal growth of 1918 virus in the lower respiratory tract of ferrets. Proc Natl Acad Sci U S A. 106: 588-592, 2009.
  2. Fan S, Deng G, Tian G, Suo Y, Song J, Jiang Y, Bu Z, Kawaoka Y & Chen H. Two amino acid residues within the matrix protein M1 correlate with the virulence of H5N1 avian influenza viruses in mice. Virology in press
  3. Murakami S, Iwasa A, Iwatasuki-Horimoto K, Ito M, Kiso M, Kida H, Takada A, Nidom CA, Le MQ, Yamada S, Imai H, Sakai-Tagawa Y, Kawaoka Y & Horimoto T. Cross-clade protective immunity of H5N1 influenza vaccines in a mouse model. Vaccine 26, 6398-6404, 2008
  4. Murakami S, Horimoto T, Le MQ, Nidom CA, Chen H, Muramoto Y, Yamada S, Iwasa A Iwatsuki-Horimoto K, Shimojima M, Iwata A & Kawaoka Y. Growth determinants for H5N1 influenza vaccine seed viruses in MDCK cells. J Virol 82, 10502-10509, 2008
  5. Hao L, Sakurai A, Watanabe T, Sorensen E, Nidom CA, Newton MA, Ahlquist P & Kawaoka Y. Drosophila RNAi screen identifies host genes important for influenza virus replication. Nature 454, 890-893, 2008
  6. Iwatsuki-Horimoto K, Hatta Y, Hatta M, Muramoto Y, Chen H, Kawaoka Y & Horimoto T. Limited compatibility between the RNA polymerase components of influenza virus type A and B. Virus Res 135, 161-165, 2008
  7. Jiao P, Tian G, Li Y, Deng G, Jiang Y, Liu C, Liu W, Bu Z, Kawaoka Y & Chen H. A single amino acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice. J Virol 82, 1146-1154, 2008
  8. Zhu Q, Yang H, Chen W, Cao W, Zhong G, Jiao P, Deng G, Yu K, Yang C, Bu Z, Kawaoka Y & Chen H. A naturally occurring deletion in its NS gene contributes to the attenuation of an H5N1 swine influenza virus in chickens. J Virol 82, 220-228, 2008
  9. Hatta M, Hatta Y, Kim JH, Watanabe S, Shinya K & Kawaoka Y. Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice. PLoS Pathog 3, 1374-1379, 2007
  10. Yamada S, Suzuki Y, Suzuki T, Le MQ, Nidom CA, Sakai-Tagawa Y, Muramoto Y, Ito M, Kiso M, Horimoto T, Shinya K, Sawada T, Kiso K, Usui T, Murata T, Lin Y, Hay A, Haire LF, Stevens DJ, Russell RJ, Gamblin SJ, Skehel JJ & Kawaoka Y. Hemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. Nature 444, 378-382, 2006
  11. Chen H, Li Y, Li Z, Shi J, Shinya K, Deng G, Qi Q, Tian G, Fan S, Zhao H, Sun Y & Kawaoka Y. Properties and dissemination of H5N1 viruses isolated during an influenza outbreak in migratory waterfowl in western China. J Virol 80, 5976-5983, 2006
  12. Shinya K, Ebina M, Yamada S, Ono M, Kasai N & Kawaoka Y. Influenza virus receptors in the human airway. Nature 440, 435-436, 2006

学会発表

  1. Murakami S, Horimoto T, Muramoto Y, Yamada S, Iwasa A, Iwatsuki-Horimoto K, Shimojima M & Kawaoka Y. Growth determinants for H5N1 influenza vaccine seed viruses in MDCK cells. August 10-15, 2008. Istanbul Convention and Exhibition Center, Istanbul, Turkey. XIV. International Congress of Virology.
  2. Shimizu K, Li C, Muramoto Y, Yamada S, Chen H & Kawaoka Y. The NP and M segments of H5N1 influenza viruses are responsible for dominance in embryonated eggs. September 7-11, 2008. The Hyogo Prefecture Awaji Yumebutai International Conference Center, Awaji, Japan. The 8th Awaji International Forum on Infection and Immunity.
  3. Muramoto Y, Itoh Y, Tamura D, Sakai-Tagawa Y, Imai H, Okamoto K, Ishigaki I, Shinya K, Le MQ, Ogasawara K & Kawaoka Y. Comparison of pathogenicity of H5N1 influenza viruses in macaques. September 7-11, 2008. The Hyogo Prefecture Awaji Yumebutai International Conference Center, Awaji, Japan. The 8th Awaji International Forum on Infection and Immunity.
  4. Takano R, Yamada S, Nidom CA, Sakai-Tagawa Y, Muramoto Y, Suzuki T, Suzuki Y & Kawaoka Y. H5N1 influenza viruses from pigs in Indonesia. September 7-11, 2008. The Hyogo Prefecture Awaji Yumebutai International Conference Center, Awaji, Japan. The 8th Awaji International Forum on Infection and Immunity.
  5. Yamada S, Suzuki Y, Suzuki T, Le MQ, Nidom CA, Sakai-Tagawa Y, Muramoto Y, Ito M, Kiso M, Horimoto T, Shinya K, Sawada T, Kiso M, Usui T, Murata T, Chen H, Lin Y, Hay A, Haire LF, Stevens DJ, Russell RJ, Gamblin SJ, Skehel JJ & Kawaoka Y. Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. September 7-11, 2008. The Hyogo Prefecture Awaji Yumebutai International Conference Center, Awaji, Japan. The 8th Awaji International Forum on Infection and Immunity.
  6. Muramoto Y, Shinya K, Gao Y, Deng G, Fan S, Zhu Q, Noda T, Tamura D, Iwatsuki-Horimoto K, Ito H, Ito T, Chen H & Kawaoka Y. Pathogenesis of an H5N1 influenza virus isolated from a human in China in rhesus macaques. September 1-5, 2007. The Hyogo Prefecture Awaji Yumebutai International Conference Center, Awaji, Japan. The 7th Awaji International Forum on Infection and Immunity.
  7. Yamada S, Suzuki Y, Suzuki T, Le MQ, Nidom CA, Sakai-Tagawa Y, Muramoto Y, Ito M, Kiso M, Horimoto T, Shinya K, Sawada T, Kiso M, Usui T, Murata T, Lin Y, Hay A, Haire LF, Stevens DJ, Russell RJ, Gamblin SJ, Skehel JJ & Kawaoka Y. Haemaggluinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. June 17-23, 2007. Metro Toronto Convention Centre, Tronto Canada. Options for the Control of Influenza VI.

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ホーム生物物理研究所微生物研究所ハルビン獣医研究所北京プロジェクトオフィス
The Institute of Medical Science, The University of Tokyo