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- I. Analyses of primate lentiviruses
A. Functional analyses
(1) Analysis of envelope protein: biosynthesis, membrane topology,
and fusion mechanism
(2) Intracellular kinesis of viral proteins (Env , Gag, Vpr/x)
(3) Effects of Vpr/x on cell function
B. Structural analyses
Gag, Vpr, and Vpx by X-ray crystallography
- II. Protein engineering
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